This study investigates gap solitons and their stability in Bose-Einstein condensates confined in Moiré optical lattices with distinct twisted angles. The results demonstrate that the twisted angle significantly modulates the Moiré periodicity and the flatness of low bands. For sufficiently large angular differences, smaller twisted angles generally lead to larger Moiré periods and flatter low bands, though this trend becomes less consistent at minimal angular differences. Moreover, smaller twisted angles yield more complex potential structures, which modify gap positions and widths, consequently affecting the properties of gap solitons. Using the Newton-conjugate gradient method, we identify various types of solitons in Moiré lattice with four different twisted angles, observing that solitons can exist over a broader range of potential depths at smaller twisted angles. The density distributions of solitons exhibit markedly different behaviors in different gaps: in the semi-infinite gap dominated by attractive interactions, deeper potentials lead to reduced soliton density, whereas in the first gap governed by repulsive interactions, deeper potentials enhance soliton density distributions. Linear stability analysis and nonlinear dynamical evolution results indicate that solitons found in the first gap(including both single-humped and multi-humped structures) demonstrate robust dynamical stability, whereas in the semi-infinite gap, single-humped solitons maintain good stability, while closely separated multi-humped in-phase solitons tend to be unstable, with enhanced stability observed for solitons located closer to the band edges. This work provides a theoretical foundation for manipulating nonlinear solitons in Moiré superlattices.