A quantum shortcut to adiabaticity scheme based on physics-informed neural networks is proposed in this work. Compared with traditional shortcut to adiabaticity technology, our method innovatively integrates machine learning methods by employing parameterized physics-informed neural networks to solve parameterized differential equations. The neural networks serve as an approximating function for quantum adiabatic evolution processes, while incorporating parameter-dependent differential equations and various physical constraints as components of the loss function. Through networks training, we effectively simulate quantum system dynamics and derive the driving control field for population inversion. Numerical simulations show that the quantum system can achieve rapid population inversion within significantly reduced time while maintaining high fidelity and exceptional robustness against parameter fluctuations. The neural networks exhibit remarkable computational capabilities, particularly suitable for generating control functions in complex quantum systems. Compared with conventional counter-diabatic driving and transitionless quantum driving methods, this PINN-based framework not only achieves better control performance but also provides the improved practicality for experimental implementations. The success of this method demonstrates its promising applications in quantum control tasks, including but not limited to quantum state preparation, quantum gate optimization, and adiabatic quantum computing acceleration.