LIU Fan; JIANG Yuancheng; GUO Hua

doi:10.7498/aps.74.20250235

Abstract

Diffusion-weighted magnetic resonance imaging (DWI) holds significant value in neuroscience and clinical disease diagnosis. The most commonly used single-shot echo-planar imaging (EPI) for DWI is affected by static magnetic field (B₀) inhomogeneity and $\rm T_2/T_2^*$ decay, leading to geometric distortion, low signal-to-noise ratio (SNR), etc. To solve these problems, researchers have developed more advanced high-resolution diffusion MRI techniques. This article comprehensively reviews these imaging methods. In the context of echo-planar imaging (EPI), this review covers multi-shot EPI-based DWI techniques, including readout-segmented EPI (RS-EPI), interleaved EPI (iEPI), point spread function-encoded EPI (PSF-EPI), and echo-planar time-resolved imaging (EPTI). These methods effectively reduce or eliminate geometric distortions while improving SNR and spatial resolution. Additionally, the combination of multi-shot EPI with simultaneous multi-slice (SMS) acquisition can shorten scan time, which is also briefly discussed in this article. Compared with EPI, spiral imaging offers higher SNR and sampling efficiency but is more sensitive to B₀ inhomogeneity. In the spiral imaging section, we review single-shot spiral DWI and multi-shot spiral DWI, as well as their integration with SMS techniques. This article emphasizes the concepts, acquisition strategies, and reconstruction methods of these imaging techniques. Finally, we discuss the challenges and future directions of high-resolution diffusion imaging, including 3D DWI, body DWI, magnetic field probes, ultra-high gradient systems, and ultra-high-field MRI systems.

Keywords:

Authors and contacts

Corresponding author: GUO Hua, huaguo@mail.tsinghua.edu.cn

FullText HTML

References

[1]
[2]
[3]
[4]
[5]
[6]
[7]
[8]
[9]
[10]
[11]
[12]
[13]
[14]
[15]
[16]
[17]
[18]
[19]
[20]
[21]
[22]
[23]
[24]
[25]
[26]
[27]
[28]
[29]
[30]
[31]
[32]
[33]
[34]
[35]
[36]
[37]
[38]
[39]
[40]
[41]
[42]
[43]
[44]
[45]
[46]
[47]
[48]
[49]
[50]
[51]
[52]
[53]
[54]
[55]
[56]
[57]
[58]
[59]
[60]
[61]
[62]
[63]
[64]
[65]
[66]
[67]
[68]
[69]
[70]
[71]
[72]
[73]
[74]
[75]
[76]
[77]
[78]
[79]
[80]
[81]
[82]
[83]
[84]
[85]
[86]
[87]
[88]
[89]
[90]
[91]
[92]
[93]
[94]
[95]
[96]
[97]
[98]
[99]
[100]
[101]
[102]
[103]
[104]
[105]
[106]
[107]
[108]
[109]
[110]
[111]
[112]
[113]
[114]
[115]
[116]
[117]
[118]
[119]
[120]
[121]
[122]
[123]
[124]
[125]
[126]
[127]
[128]
[129]
[130]
[131]
[132]
[133]
[134]
[135]
[136]
[137]
[138]
[139]
[140]
[141]
[142]
[143]
[144]
[145]
[146]
[147]
[148]
[149]
[150]
[151]
[152]
[153]
[154]
[155]
[156]
[157]
[158]
[159]
[160]
[161]
[162]
[163]
[164]
[165]
[166]
[167]

Cited By

DownLoad: Full-Size Img PowerPoint

DownLoad: Full-Size Img PowerPoint

DownLoad: Full-Size Img PowerPoint

DownLoad: Full-Size Img PowerPoint

DownLoad: Full-Size Img PowerPoint

DownLoad: Full-Size Img PowerPoint

DownLoad: Full-Size Img PowerPoint

DownLoad: Full-Size Img PowerPoint

DownLoad: Full-Size Img PowerPoint

DownLoad: Full-Size Img PowerPoint

DownLoad: Full-Size Img PowerPoint

DownLoad: Full-Size Img PowerPoint

[1]
[2]
[3]
[4]
[5]
[6]
[7]
[8]
[9]
[10]
[11]
[12]
[13]
[14]
[15]
[16]
[17]
[18]
[19]
[20]
[21]
[22]
[23]
[24]
[25]
[26]
[27]
[28]
[29]
[30]
[31]
[32]
[33]
[34]
[35]
[36]
[37]
[38]
[39]
[40]
[41]
[42]
[43]
[44]
[45]
[46]
[47]
[48]
[49]
[50]
[51]
[52]
[53]
[54]
[55]
[56]
[57]
[58]
[59]
[60]
[61]
[62]
[63]
[64]
[65]
[66]
[67]
[68]
[69]
[70]
[71]
[72]
[73]
[74]
[75]
[76]
[77]
[78]
[79]
[80]
[81]
[82]
[83]
[84]
[85]
[86]
[87]
[88]
[89]
[90]
[91]
[92]
[93]
[94]
[95]
[96]
[97]
[98]
[99]
[100]
[101]
[102]
[103]
[104]
[105]
[106]
[107]
[108]
[109]
[110]
[111]
[112]
[113]
[114]
[115]
[116]
[117]
[118]
[119]
[120]
[121]
[122]
[123]
[124]
[125]
[126]
[127]
[128]
[129]
[130]
[131]
[132]
[133]
[134]
[135]
[136]
[137]
[138]
[139]
[140]
[141]
[142]
[143]
[144]
[145]
[146]
[147]
[148]
[149]
[150]
[151]
[152]
[153]
[154]
[155]
[156]
[157]
[158]
[159]
[160]
[161]
[162]
[163]
[164]
[165]
[166]
[167]

[1]	Wen Ya-Fei, Tian Jian-Feng, Wang Zhi-Qiang, Zhuang Yuan-Yuan. Fiber-cavity enhanced and high-fidelity optical memory in cold atom ensemble. Acta Physica Sinica, 2023, 72(6): 060301. doi: 10.7498/aps.72.20222178
[2]	Yu Jun-Jin, Guo Xing-Yi, Sui Yi-Hui, Song Jian-Ping, Ta De-An, Mei Yong-Feng, Xu Kai-Liang. Ultrafast ultrasound localization microscopy method for spinal cord mircovasculature imaging. Acta Physica Sinica, 2022, 71(17): 174302. doi: 10.7498/aps.71.20220629
[3]	Sui Yi-Hui, Guo Xing-Yi, Yu Jun-Jin, Alexander A. Solovev, Ta De-An, Xu Kai-Liang. Accelerating super-resolution ultrasound localization microscopy using generative adversarial net. Acta Physica Sinica, 2022, 71(22): 224301. doi: 10.7498/aps.71.20220954
[4]	Sun Sheng, Wang Chao, Shi Hao-Dong, Fu Qiang, Li Ying-Chao. Aberration correction of aperture-divided off-axis simultaneous polarization super-resolution imaging optical system. Acta Physica Sinica, 2022, 71(21): 214201. doi: 10.7498/aps.71.20220946
[5]	Xiang Peng-Cheng, Cai Cong-Bo, Wang Jie-Chao, Cai Shu-Hui, Chen Zhong. Super-resolved reconstruction method for spatiotemporally encoded magnetic resonance imaging based on deep neural network. Acta Physica Sinica, 2022, 71(5): 058702. doi: 10.7498/aps.71.20211754
[6]	Zhong Zhi, Zhao Wan-Ting, Shan Ming-Guang, Liu Lei. Telecentric in-line-and-off-axis hybrid digital holographic high-resolution reconstruction method. Acta Physica Sinica, 2021, 70(15): 154202. doi: 10.7498/aps.70.20210190
[7]	Liu Liang-You, Gao Song, Li Sha, Li Zhao-Tong, Xia Yi-Fan. Research progress of diffusion sensitive gradient field encoding schemes in magnetic resonance diffusion tensor imaging. Acta Physica Sinica, 2020, 69(3): 038702. doi: 10.7498/aps.69.20191346
[8]	Lü Hao-Chang, Zhao Yun-Chi, Yang Guang, Dong Bo-Wen, Qi Jie, Zhang Jing-Yan, Zhu Zhao-Zhao, Sun Yang, Yu Guang-Hua, Jiang Yong, Wei Hong-Xiang, Wang Jing, Lu Jun, Wang Zhi-Hong, Cai Jian-Wang, Shen Bao-Gen, Yang Feng, Zhang Shen-Jin, Wang Shou-Guo. High resolution imaging based on photo-emission electron microscopy excited by deep ultraviolet laser. Acta Physica Sinica, 2020, 69(9): 096801. doi: 10.7498/aps.69.20200083
[9]	Liu Fei, Wei Ya-Zhe, Han Ping-Li, Liu Jia-Wei, Shao Xiao-Peng. Design of monocentric wide field-of-view and high-resolution computational imaging system. Acta Physica Sinica, 2019, 68(8): 084201. doi: 10.7498/aps.68.20182229
[10]	Gao Qiang, Wang Xiao-Hua, Wang Bing-Zhong. Far-field super-resolution imaging based on wideband stereo-metalens. Acta Physica Sinica, 2018, 67(9): 094101. doi: 10.7498/aps.67.20172608
[11]	Zhu Xue-Tao, Guo Jian-Dong. Development of novel high-resolution electron energy loss spectroscopy and related studies on surface excitations. Acta Physica Sinica, 2018, 67(12): 127901. doi: 10.7498/aps.67.20180689
[12]	Li Jie, Zhu Jing-Ping, Zhang Yun-Yao, Liu Hong, Hou Xun. Spectral zooming birefringent imaging spectrometer. Acta Physica Sinica, 2013, 62(2): 024205. doi: 10.7498/aps.62.024205
[13]	Zhang Wen-Xi, Xiang Li-Bin, Kong Xin-Xin, Li Yang, Wu Zhou, Zhou Zhi-Sheng. Resolution of coherent field imaging technique. Acta Physica Sinica, 2013, 62(16): 164203. doi: 10.7498/aps.62.164203
[14]	Wang Fang, Zhao Xing, Yang Yong, Fang Zhi-Liang, Yuan Xiao-Cong. Comparison of the resolutions of integral imaging three-dimensional display based on human vision. Acta Physica Sinica, 2012, 61(8): 084212. doi: 10.7498/aps.61.084212
[15]	Lu Jing, Li Hao, He Yi, Shi Guo-Hua, Zhang Yu-Dong. Superresolution in adaptive optics confocal scanning laser ophthalmoscope. Acta Physica Sinica, 2011, 60(3): 034207. doi: 10.7498/aps.60.034207
[16]	Wu Dan, Tao Chao, Liu Xiao-Jun. Study of the resolution of limited-view photoacoustic tomography. Acta Physica Sinica, 2010, 59(8): 5845-5850. doi: 10.7498/aps.59.5845
[17]	Dai Qiu-Sheng, Qi Yu-Jin. Spatial resolution of pinhole single photon emission computed tomography imaging. Acta Physica Sinica, 2010, 59(2): 1357-1365. doi: 10.7498/aps.59.1357
[18]	Huo Bing-Zhong, Yuan Jing-He, Shang Ying, Meng Chun-Ning. Spherical superlens analysed by dyadic Green’s function. Acta Physica Sinica, 2010, 59(11): 8178-8183. doi: 10.7498/aps.59.8178
[19]	Xiang Liang-Zhong, Xing Da, Guo Hua, Yang Si-Hua. High resolution fast digital photoacoustic CT for breast cancer diagnosis. Acta Physica Sinica, 2009, 58(7): 4610-4617. doi: 10.7498/aps.58.4610
[20]	Zhao Gui-Min, Lu Ming-Zhu, Wan Ming-Xi, Fang Li. Study of vibro-acoustography with high spatial resolution based on sector array transducers. Acta Physica Sinica, 2009, 58(9): 6596-6603. doi: 10.7498/aps.58.6596

Catalog

Vol. 74, Issue 11 - 2025-06-05

Metrics

Abstract views: 344
PDF Downloads: 27
Cited By: 0

姓名
邮箱
手机号码
标题
留言内容
验证码

Search

Article

留言板

Abstract

Authors and contacts

Corresponding author: GUO Hua, huaguo@mail.tsinghua.edu.cn

FullText HTML

References

Cited By

Catalog

Metrics

Authors

Referees

About Journal

About

Search

Article

留言板

Abstract

Authors and contacts

Corresponding author: GUO Hua, huaguo@mail.tsinghua.edu.cn

FullText HTML

References

Cited By

Catalog

Metrics

Publishing process

Authors

Referees

About Journal

About